One goal. One system.
Building Europe’s reference framework for autonomous AI.
CEREBRA-AI is developing a shared intelligence layer that enables AI capabilities to work together, learn from experience and improve as one system, within limits set by people.
The strategic goal
The ambition is to establish a European reference framework for autonomous AI: a common foundation through which independently developed capabilities become more useful together, and improvements can transfer between systems.
Models, tools and environments connect through shared interfaces. CEREBRA-AI’s research focuses on how the system chooses and coordinates them, learns from their outcomes and qualifies changes before they are used more widely.
Autonomy within limits set by people
People define the task, permissions, resource limits and required approvals. Within that scope, the framework is designed to select capabilities, carry out a plan, respond to failures and ask for help when needed.
Outcomes feed a separate learning and evaluation process. Proposed improvements must be tested before they become eligible for wider use, with a route to restore a previous version.
Three ambitions, one foundation
| Ambition | What CEREBRA-AI is working towards |
|---|---|
| Scientific | Advance reasoning and continual learning; test whether useful improvements transfer between systems. |
| Technological | Develop an autonomous runtime, shared interfaces and developer tools, with evidence supporting execution and change. |
| Commercial | Establish a reusable framework that partners can build on through specialist capabilities, sector applications and services. |
Research that strengthens the whole system
- Reasoning connects learned patterns with explicit knowledge, rules and checks.
- Continual learning studies adaptation and the retention of earlier capabilities.
- Grounded interaction connects the framework to people, robots, digital twins and workflows.
- Trust research makes provenance, explanations, uncertainty and oversight part of the same system.
Nine pilots. A common foundation.
Manufacturing, healthcare, mobility, energy, agriculture, coastal resilience, community care and knowledge work bring different demands to the research. The nine planned pilots will test reusable capabilities and shared interfaces in these settings.
A gain in one pilot raises a further question: can another system reproduce it, with compatible components and its own operating constraints?
An ambition to earn through evidence
The project will compare complete-task outcomes using strong baselines, matched capabilities and resource budgets. Evaluation will examine recovery, retained skills, human intervention and resource use alongside performance.
The framework is under development. Its reference status will depend on reproducible results, useful adoption and a technical foundation that others can build on.
The project at a glance
| Programme | CEREBRA-AI |
|---|---|
| Funding | €14,997,790 in European Union funding |
| Duration | 48 months · 01/09/2026–31/08/2030 |
| Collaboration | 34 participating organisations across 14 countries |
| Validation | Nine planned pilot use cases |
| Coordination | Neuralio AI, Greece |
| Grant agreement | 101299046 |
European Union funding
CEREBRA-AI is funded by the European Union under the Horizon Europe programme, topic HORIZON-CL4-2025-04-DIGITAL-EMERGING-07 (Enhanced Learning Strategies for General Purpose AI: Advancing GenAI4EU), Grant Agreement No 101299046.
Funded by the European Union. Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of the European Union or the European Health and Digital Executive Agency (HaDEA). Neither the European Union nor the granting authority can be held responsible for them.